NACI Literature Review on the Comparative Effectiveness and Immunogenicity of Subunit and Split Virus Inactivated Influenza Vaccines in Adults 65 Years of Age and Older
Subunit and split virus inactivated influenza vaccines are two commonly used types of seasonal influenza vaccines, and continue to dominate the market in Canada. Although these two formulations of influenza vaccine have been available for many decades, NACI has not previously conducted a literature review to investigate the comparative vaccine effectiveness of these different formulations. A difference in vaccine effectiveness between these formulations would be especially important for older adults (65 years of age or older), since there is evidence that older adults experience more severe illness due to influenza and have reduced vaccine effectiveness compared to younger adults. To address this gap, NACI conducted a literature review to examine the vaccine effectiveness and immunogenicity of unadjuvanted, standard dose subunit inactivated influenza vaccines compared to unadjuvanted, standard dose split virus inactivated influenza vaccines in adults 65 years of age and older.
Poster: Immunization against pertussis during pregnancy is safe and helps reduce the risk of disease in infants.
Immunization rates in Canada are suboptimal. Strategies such as making immunization mandatory for child care or school entry and financial incentives are used in other countries. Additional strategies that could work in the Canadian context include requiring accurate immunization records at school entry, implementing immunization registries at the provincial/territorial level, educating parents and school-aged children about vaccine-preventable diseases and making it more convenient for parents to ensure their children are fully immunized.
Questions-réponses sur l’immunisation contre la coqueluche avec le vaccin dcaT pendant la grossesse au Canada
Reasons for non-vaccination: Parental vaccine hesitancy and the childhood influenza vaccination school pilot programme in England
The aim of this study was to explore the reasons some parents decided not to vaccinate their child against influenza as part of the pilot programme offered in [UK] schools.
Selon les données probantes examinées et résumées dans la présente déclaration de son comité consultatif, le Comité consultatif de l’immunisation fait des recommandations relativement à l’utilisation du VVVCZ recommandé par le passé et du VRZ récemment autorisé au niveau de la population et au niveau individuel.
Repeated influenza vaccination for preventing severe and fatal influenza infection in older adults: a multicentre case–control study
The effectiveness of repeated vaccination for influenza to prevent severe cases remains unclear. Researchers evaluated the effectiveness of influenza vaccination on preventing admissions to hospital for influenza and reducing disease severity.